Symptoms of an adverse effect include lethargy depression pale mucous membranes abnormal vaginal discharge loss of appetite and bleeding from the gastrointestinal and urinary tract.
Des for dogs side effects.
Other side effects include signs of being in heat including vaginal discharge or spotting infection of the uterus in intact female dogs pyometra diarrhea vomiting lack of energy increased water consumption increased urination and feminization of male dogs.
Estrogenic effects such as swollen vulva mammary hyperplasia and vulvar discharge occurred frequently in all dogs that received incurin tablets and increased in a dose dependent manner.
On gross necropsy all dogs treated with incurin tablets had enlarged vulvas except 1 dog that received 2 mg per day.
Side effects are more common in older animals.
The use of diethylstilbestrol for the prevention of pregnancy is no longer recommended due to.
Diethylstilbestrol is a synthetic estrogen hormone used in the treatment of urinary incontinence in female dogs and cats benign prostatic hypertrophy prostate enlargement in male dogs and the prevention of pregnancy after mismating in dogs and cats.
Diethylstilbestrol can also increase the risk of uterine infections pyometra when given to intact unspayed female dogs.
Des is also sometimes used to treat some forms of prostate disease and to induce estrus.
Steroids prednisone prednisolone dexamethasone etc and nonsteroidal anti inflammatory medications carprofen deracoxib and firocoxib to name a few are known to increase a pet s risk of developing gastrointestinal ulcers which can lead to vomiting and or diarrhea that may contain blood.
Some of the common side effects of diethylstilbestrol in dogs include the following.
Des can be used to induce abortion a morning after pill in dogs but it is not as reliable as other abortion methods.
These include vulvar swelling excessive drinking and urination appetite loss and vomiting.
Vaginal discharge bleeding from the gastrointestinal system loss of appetite weakness discoloration of the mucus membranes.
Precautions des and other estrogens should not be used during pregnancy as it has been shown to cause fetal malformations.
Side effects are uncommon if used at the appropriate lowest effective dose but may include mild vaginal spotting.
However while incurin is generally well tolerated some dogs do experience side effects while taking it.